| Strain Name | C57BL/6JNifdc DIO | Common Name | B-DIO mice |
| Background | C57BL/6JNifdc | Catalog number |
112938 |
| Aliases | / | ||
Body weight of B-DIO mice. Male C57BL/6JNifdc mice, aged 5 weeks, were put on a diet consisting of 60 kcal% high-fat feed. Their weights were recorded weekly from a total of 116 mice. The data is presented as Mean ± SD. After being fed with the high-fat diet for 10 weeks, the average weight of the B-DIO mice exceeded 40g.
Glucose tolerance tests
In vivo efficacy of Semaglutide in B-DIO mice
The hypoglycemic and lipid-lowering effects of Semaglutide in B-DIO mice. (A) Blood glucose change after Semaglutide treatment. (B) Glucose tolerance ability after treatment. (C) Area under curve of B. (D-G) Blood biochemical analysis after treatment. Data are expressed as mean ± SEM. N=10 mice per group. *p<0.05, **p<0.01, ***p<0.001 ,****p<0.0001.
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